FIBRIN GEL AS A SCAFFOLD FOR SKIN SUBSTITUTE – PRODUCTION AND CLINICAL EXPERIENCE
نویسندگان
چکیده
منابع مشابه
Fibrin gel as a scaffold for skin substitute – production and clinical experience.
The purpose of this study was to create a fibrin-based human skin substitute in vitro with epidermal and dermal component and to assess its healing potential in deep partial and full thickness burns. Fibrin scaffolds were prepared from commercial fibrin glue kits. Human fibroblasts were cultured in fibrin gel. Human keratinocytes were seeded on the top of the gel. Viability of cells was determi...
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Due to the increasing needs for organ transplantation and a universal shortage of donated tissues, tissue engineering emerges as a useful approach to engineer functional tissues. Although different synthetic materials have been used to fabricate tissue engineering scaffolds, they have many limitations such as the biocompatibility concerns, the inability to support cell attachment, and undesirab...
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A variety of skin substitutes that restore epidermal and dermal structures are currently available on the market. However, the main focus in research and clinical application lies on dermal and epidermal substitutes whereas the development of a subcutaneous replacement (hypodermis) is often disregarded. In this study we used fibrin sealant as hydrogel scaffold to generate a three-layered skin s...
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ژورنال
عنوان ژورنال: Acta Clinica Croatica
سال: 2016
ISSN: 0353-9466
DOI: 10.20471/acc.2016.55.02.15